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KMID : 0363320190400061145
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Journal of Korean Oriental Internal Medicine
2019 Volume.40 No. 6 p.1145 ~ p.1151
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Effect of Herbal Medicine on Liver Function in Korean Medical Hospital Inpatients: A Retrospective Chart Review
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Seo Hyung-Bum
Seo Hee-Jeong
Shim So-Hyun
Lee Chan
Cho Im-Hak
Han Chang-Woo
Kim So-Yeon
Choi Jun-Yong
Park Seong-Ha
Yun Young-Ju
Hong Jin-Woo
Kwon Jung-Nam
Lee In
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Abstract
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Objectives: The purpose of this study was to investigate liver function test results in admitted patients before and after herbal treatment.
Methods: 54 subjects admitted to hospital had liver function tests (aspartate aminotransferase, alanine amino transferase, alkaline phosphatase, total bilirubin) before and after herbal treatment from 1 March 2017 to 30 June 2019.
Results: Aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase were not significantly changed (p>0.05). On admission, 11 patients had abnormal liver function, while seven patients had abnormal results in alkaline phosphatase upon discharge. Three of the seven were normal when they were hospitalized.
Conclusions: This study suggests that herbal treatment may have no effect on liver injury.
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KEYWORD
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herbal medicine, liver function, drug-induced liver injury
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